Journal: Diabetes

Article Title: Prenatal Programming of Metabolic Syndrome in the Common Marmoset Is Associated With Increased Expression of 11β-Hydroxysteroid Dehydrogenase Type 1

doi: 10.2337/db09-0873

Figure Lengend Snippet: Effect of prenatal dexamethasone on offspring body weight. Graph shows body weight at different ages in offspring of mothers that received vehicle (Control), or dexamethasone during early (Early-DEX) or late (Late-DEX) pregnancy. * P < 0.05 compared with control animals.

Article Snippet: Dexamethasone tablets (0.5, 1.5, or 4 mg; Jenapharm, Jena, Germany) were dissolved in 0.4 ml of tap water and mixed with 1.6 ml NutriCal (Albrecht, Aulendorf, Germany).

Techniques: Control

Journal: Diabetes

Article Title: Prenatal Programming of Metabolic Syndrome in the Common Marmoset Is Associated With Increased Expression of 11β-Hydroxysteroid Dehydrogenase Type 1

doi: 10.2337/db09-0873

Figure Lengend Snippet: Effect of prenatal dexamethasone on 11β-HSD1 expression in the liver. Hepatic 11β-HSD1 mRNA expression was measured by real-time PCR in 4-month-old ( A ) and 24-month-old ( B ) offspring of mothers that received vehicle (Control) or dexamethasone during early (Early-DEX) or late (Late-DEX) pregnancy. 11β-HSD1 enzyme activity was assessed in 24-month-old livers ( C ). Results represent mRNA expression relative to control animals. * P < 0.05 compared with control animals.

Article Snippet: Dexamethasone tablets (0.5, 1.5, or 4 mg; Jenapharm, Jena, Germany) were dissolved in 0.4 ml of tap water and mixed with 1.6 ml NutriCal (Albrecht, Aulendorf, Germany).

Techniques: Expressing, Real-time Polymerase Chain Reaction, Control, Activity Assay

Journal: Diabetes

Article Title: Prenatal Programming of Metabolic Syndrome in the Common Marmoset Is Associated With Increased Expression of 11β-Hydroxysteroid Dehydrogenase Type 1

doi: 10.2337/db09-0873

Figure Lengend Snippet: 11β-HSD1 expression in adipose tissue and pancreas. 11β-HSD1 mRNA expression was measured in subcutaneous fat ( A ), peritoneal fat ( B ) and pancreas ( C ) of in 24-month-old offspring of mothers that received vehicle (Control), or dexamethasone during early (Early-DEX) or late (Late-DEX) pregnancy. Results represent mRNA expression relative to control animals. * P < 0.05.

Article Snippet: Dexamethasone tablets (0.5, 1.5, or 4 mg; Jenapharm, Jena, Germany) were dissolved in 0.4 ml of tap water and mixed with 1.6 ml NutriCal (Albrecht, Aulendorf, Germany).

Techniques: Expressing, Control

Journal: Diabetes

Article Title: Prenatal Programming of Metabolic Syndrome in the Common Marmoset Is Associated With Increased Expression of 11β-Hydroxysteroid Dehydrogenase Type 1

doi: 10.2337/db09-0873

Figure Lengend Snippet: Effect of prenatal dexamethasone on PEPCK expression in the liver. Hepatic PEPCK mRNA ( A ) and activity ( B ) were measured in 24-month-old offspring of mothers that received vehicle (Control) or dexamethasone during early (Early-DEX) or late (Late-DEX) pregnancy. Results represent mRNA expression or enzyme activity relative to control animals. * P < 0.05 compared with control animals.

Article Snippet: Dexamethasone tablets (0.5, 1.5, or 4 mg; Jenapharm, Jena, Germany) were dissolved in 0.4 ml of tap water and mixed with 1.6 ml NutriCal (Albrecht, Aulendorf, Germany).

Techniques: Expressing, Activity Assay, Control

Journal: Diabetes

Article Title: Prenatal Programming of Metabolic Syndrome in the Common Marmoset Is Associated With Increased Expression of 11β-Hydroxysteroid Dehydrogenase Type 1

doi: 10.2337/db09-0873

Figure Lengend Snippet: Effect of dexamethasone on glucocorticoid receptor expression. Tissue glucocorticoid receptor mRNA was measured in liver ( A ), subcutaneous fat ( B ), peritoneal fat ( C ), and pancreas ( D ) by real-time PCR in 24-month-old offspring of mothers that received vehicle (Control) or dexamethasone during early (Early-DEX) or late (Late-DEX) pregnancy. Results are expressed as mRNA expression relative to control animals.

Article Snippet: Dexamethasone tablets (0.5, 1.5, or 4 mg; Jenapharm, Jena, Germany) were dissolved in 0.4 ml of tap water and mixed with 1.6 ml NutriCal (Albrecht, Aulendorf, Germany).

Techniques: Expressing, Real-time Polymerase Chain Reaction, Control

Journal: Aging (Albany NY)

Article Title: A catalogue of omics biological ageing clocks reveals substantial commonality and associations with disease risk

doi: 10.18632/aging.203847

Figure Lengend Snippet: Multiple omics make accurate ageing clocks.

Article Snippet: Finally, the UK Biobank [ ] (UKB) was used to test the Clinomics and DEXA clocks trained in ORCADES.

Techniques: